Author

Pedro Sánchez-Sánchez

Institute for Research in BiomedicineORCID 0000-0002-4846-1813Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:clustering· 3 Approach:statistical model· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

Alejo E Rodriguez-FraticelliiD· 3 shared Indranil SinghiD· 3 shared Daniel Fernández-PéreziD· 2 shared Agostina BianchiiD· 1 shared Alex Maya Pombo· 1 shared Andrea PolazziiD· 1 shared Ansuman T. SatpathyiD· 1 shared Caleb A. LareauiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCancer Biology

Alejo E Rodriguez-FraticelliORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 25, 2026

Leukemia stem cell expansion cultures reveal clonal drivers of leukemogenesis and therapy response

Indranil Singh, Andrea Polazzi, Alex Maya Pombo…·Alejo Rodriguez-Fraticelli

This paper develops PLSTCs to expand AML LSCs and identifies clonal drivers of leukemogenesis and therapy response through genomic and single-cell analyses.

1 citation

humanscRNA-seq

GenomicsNaturePeer-reviewedMay 21, 2025

Somatic epimutations enable single-cell lineage tracing in native hematopoiesis across the murine and human lifespan

Michael Scherer, Indranil Singh, Martina Maria Braun…·Lars Velten

This paper introduces EPI-clone, a method using DNA methylation to trace clonal lineages in hematopoiesis without genetic engineering, showing clonal complexity declines with age in mice and expands in humans.

67 citationstop 1%

mousehuman

Cancer BiologyCell stem cellPeer-reviewedFeb 25, 2025

Pre-existing stem cell heterogeneity dictates clonal responses to acquisition of cancer driver mutations

Indranil Singh, Daniel Fernández-Pérez, Pedro Sanchez Sanchez, Alejo E Rodriguez-Fraticelli

The paper develops STRACK to trace clonal gene expression and expansion dynamics in leukemia, showing pre-existing stem cell heterogeneity dictates clonal responses to cancer mutations.

28 citationstop 1%

mousescRNA-seq