Author

Alex Maya Pombo

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

Alejo Rodriguez-FraticelliiD· 2 shared Daniel Fernández-PéreziD· 2 shared Andrea PolazziiD· 1 shared Anne L. RobertsoniD· 1 shared Avik Choudhuri· 1 shared Carmen GallardoiD· 1 shared Caroline KubaczkaiD· 1 shared Celine Bauer· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

Alejo Rodriguez-FraticelliORCID

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2 papers

Recent·Most cited

Leukemia stem cell expansion cultures reveal clonal drivers of leukemogenesis and therapy response

Indranil Singh, Andrea Polazzi, Alex Maya Pombo, Marta López-Osias, Celine Bauer, Maria Guarini, Pedro Sánchez-Sánchez, Luna Goulet, Carmen Gallardo, Daniel Fernández-Pérez, Robert L. Bowman, Alejo Rodriguez-Fraticelli

This paper develops PLSTCs to expand AML LSCs and identifies clonal drivers of leukemogenesis and therapy response through genomic and single-cell analyses.

bioRxiv · Feb 25, 2026 · PreprintCancer Biology

A molecular switch: Ro5-3335 drives hematopoietic stem cell division and clonality through distinct RUNX1 binding partners

Anne L. Robertson, Yue Lü, Avik Choudhuri, Daniel Fernández-Pérez, Alex Maya Pombo, Caroline Kubaczka, Samuel J. Wattrus, Kyle D. Drake, Joseph Mandelbaum, Serine Avagyan, Song P. Yang, Rohan Bhattacharya, Rebecca J. Freeman, Victoria Chan, Megan C. Blair, , Leonard Ira Zon

This study identifies Ro5-3335 as a chemical that increases HSC clone number and clonal diversity by altering RUNX1 binding partners in zebrafish and mouse models.

bioRxiv · Jun 7, 2024 · PreprintCell Biology