Author

Maheen Alam

University of East AngliaORCID 0000-0002-4848-0782Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:plant (other)· 2 Organism:Arabidopsis· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Jonathan D. G. JonesiD· 3 shared Kamil WitekiD· 2 shared Xiao LiniD· 2 shared Ahmed Jawaad AfzaliD· 1 shared Aleksandra Wawryk-KhamdavongiD· 1 shared Andrea Carolina Olave-AchuryiD· 1 shared Anmbreen JamrozeiD· 1 shared David M. MackeyiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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3 shared papersPlant Biology

Jonathan D. G. JonesORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Diverse haplotypes at a complex Solanum americanum locus confer resistance to Phytophthora infestans and P. capsici

Robert Heal, Andrea Carolina Olave-Achury, Maria Sindalovskaya, Ruth Norkor Annang, Shuting Sun, He Zhao, Qing Liu, Long Li, Hari S. Karki, Jodie Taylor, Aleksandra Wawryk-Khamdavong, Kinga Bachowska, Matthew Smoker, Maheen Alam, Sarah E. Pottinger, , Jonathan D. G. Jones

The paper identifies two resistance genes from Solanum americanum that confer resistance to Phytophthora pathogens and shows their NLR cluster evolves in response to multiple pathogens.

The Plant Cell · Sep 1, 2026Peer-reviewedPlant Biology

Interfamily co-transfer of sensor and helper NLRs extends immune receptor functionality between angiosperms

Xiaofei Du, Maheen Alam, Kamil Witek, Lesley Milnes, James Houghton, Xiao Lin, Heekyung Ahn, Yu Long Zhang, Fuhao Cui, Wenxian Sun, Jonathan D. G. Jones, Hailong Guo

The paper demonstrates that co-transferring sensor and helper NLRs from Solanaceae to rice, soybean, and Arabidopsis can extend immune receptor functionality across plant families.

Cell · Jun 17, 2025Peer-reviewedPlant Biology

Defense-Suppressive Fragments of RIN4 generated by AvrRpt2 Participate in NDR1-dependent Activation of RPS2

Ahmed Jawaad Afzal, Maheen Alam, Jianhua Huang, Moneeza Akbar Agha, Luis da Cunha, Muneeza Iqbal Rai, Jibran Tahir, Anmbreen Jamroze, Jonathan D. G. Jones, David M. Mackey

The paper identifies non-membrane-tethered RIN4 fragments generated by AvrRpt2 that activate RPS2, requiring NDR1 and overcoming suppression by the membrane-tethered C-terminal fragment.

bioRxiv · Jun 2, 2025 · PreprintPlant Biology