Author

Enzo Tramontano

University of CagliariORCID 0000-0002-4849-0980Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:mouse· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrea R. BeccariiD· 2 shared Andrea ZalianiiD· 2 shared Daniela IaconisiD· 2 shared Francesca EspositoiD· 2 shared Jeanette ReinshageniD· 2 shared Maria KuzikoviD· 2 shared Markus Wolf· 2 shared Paola StoriciiD· 2 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Andrea R. BeccariORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 28, 2024

Screening Envelope Genes Across Primate Genomes Reveals Evolution and Diversity Patterns of Endogenous Retroviruses

Saili Chabukswar, Nicole Grandi, Elena Soddu…·Enzo Tramontano

The paper reconstructs and analyzes env genes of ERVs across 55 primate species to reveal evolutionary patterns and recombination events in Catarrhini and Platyrrhini lineages.

DOI 10.1101/2024.10.28.620668

humanmouse

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Molecular BiologybioRxivPreprintOct 11, 2023

Resolving the pharmacological redox-sensitivity of SARS-CoV-2 PLpro in drug repurposing screening enabled identification of the competitive GRL-0617 binding site inhibitor CPI-169

Maria Kuzikov, Stefano Morasso, Jeanette Reinshagen…·Andrea Zaliani

The paper identifies CPI-169 as a competitive inhibitor of SARS-CoV-2 PLpro that targets the same binding site as GRL-0617, through a drug repurposing screening approach that accounts for redox-sensitivity.

2 citations

humanexperimental assay

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Molecular BiologyACS Pharmacology & Translational SciencePeer-reviewedMar 11, 2021

Identification of inhibitors of SARS-CoV-2 3CL-Pro enzymatic activity using a small molecule in-vitro repurposing screen

Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen…·Andrea Zaliani

The paper identifies 62 new inhibitors of SARS-CoV-2 3CL-Pro through a compound repurposing screen and validates their activity using X-ray crystallography.

159 citationstop 1%

experimental assaydrug response / drug discovery

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