Design, Amino-Acid-Derived Analogues of FTY-720 and OSU-2S as PP2A Activators: Structure-Activity Relationships and Identification of Lead Compound XML-3D
Rui Yang, Noura Srour, Pankajavalli Thirugnanasambandam…·Pui-Kai Li
The paper designs and evaluates amino-acid-derived PP2A activators, identifies XML-3D as a lead compound with improved cytotoxicity compared to FTY-720 and OSU-2S.