Author

Pui‐Kai Li

The Ohio State UniversityORCID 0000-0002-4831-7213Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Enming XingiD· 2 shared Alessio MacoranoiD· 1 shared David R. ShermaniD· 1 shared Haowen JiangiD· 1 shared Hassan E. EldesoukyiD· 1 shared Jeffrey K. J. ChengiD· 1 shared Jiangbin YeiD· 1 shared Justin K. BracheiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Enming XingORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 12, 2025

The pH gradient contributes to persistence in Mycobacterium tuberculosis

Hassan E. Eldesouky, Kristin N. Adams, Justin K. Brache…·David R. Sherman

This study identifies niclosamide as a compound that induces drug tolerance in Mycobacterium tuberculosis by disrupting the pH gradient, revealing a new mechanism for persister cell formation.

DOI 10.1101/2025.09.12.675885

proteomicsexperimental assay

Pharmacology & ToxicologybioRxivPreprintJul 4, 2025

Discovery of Niclosamide Analogs with Potent Mitochondrial Uncoupling Activity with reduced toxicity

Haowen Jiang, Alessio Macorano, Enming Xing…·Pui‐Kai Li

This study develops Niclosamide analogs with improved mitochondrial uncoupling activity and reduced toxicity for cancer treatment.

DOI 10.1101/2025.07.04.663252

experimental assaydrug response / drug discovery