Author
The Ohio State UniversityORCID 0009-0001-6876-8812Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Rui Yang, Noura Srour, Pankajavalli Thirugnanasambandam…·Pui-Kai Li
The paper designs and evaluates amino-acid-derived PP2A activators, identifies XML-3D as a lead compound with improved cytotoxicity compared to FTY-720 and OSU-2S.
Junjie Zhang, Enming Xing, Xiaolin Cheng
MSACLR uses contrastive learning to map multiple sequence alignments to protein conformations, achieving better fold separation and capturing conformational variation.
Hassan E. Eldesouky, Kristin N. Adams, Justin K. Brache…·David R. Sherman
This study identifies niclosamide as a compound that induces drug tolerance in Mycobacterium tuberculosis by disrupting the pH gradient, revealing a new mechanism for persister cell formation.
Haowen Jiang, Alessio Macorano, Enming Xing…·Pui‐Kai Li
This study develops Niclosamide analogs with improved mitochondrial uncoupling activity and reduced toxicity for cancer treatment.