Jinghui Li

This study constructs a multi-tissue cell atlas of pigs, identifies cell-type-specific gene regulation, and links these to complex traits and human phenotypes.

The paper links trans-pQTLs to protein-protein interactions and GWAS loci, identifying therapeutic targets in autoimmune diseases.

The paper presents PigGTEx, a resource linking genetic variants to transcriptomic phenotypes in pigs, showing pigs' similarity to humans in gene regulation and complex traits.

This paper develops DeepGCF, a deep learning method to predict functional conservation between human and pig using epigenome and transcriptome data, showing improved performance and insights into regulatory and heritability patterns.

The paper develops LPChoose, a linear programming approach to optimize sequencing resource allocation in genotyped livestock populations for efficient haplotype coverage.