Author

Maria Cecilia Quadraccia

Bambino Gesù Children's HospitalORCID 0000-0002-4877-2793Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Anaïs Vermare· 1 shared Andrea ValentiniiD· 1 shared Biagio De AngelisiD· 1 shared Camille Combe· 1 shared Concetta QuintarelliiD· 1 shared Dongjie AniD· 1 shared Emmanuel DonnadieuiD· 1 shared Frédéric PendinoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Anaïs Vermare

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1 paper

Recent·Most cited

ImmunologyMolecular TherapyPeer-reviewedApr 4, 2026

An in vivo CRISPR screen unveils top target genes to improve CAR-T cell efficacy in a solid tumor model

Mattia Fumagalli, Dongjie An, Luca Simula…·Frédéric Pendino

This study uses an in vivo CRISPR screen to identify genes that enhance CAR-T cell efficacy in a solid tumor model, finding that disrupting REGNASE-1, SOCS1, PTPN2, and P16/NK4A improves tumor eradication.

4 citationstop 1%

humangenetic perturbation / CRISPR