Shi Yu Chan

Epigenetic and brain age across development: Performance and associations in the MIND consortium

Across 15 cohorts (birth to 24 years), 20 epigenetic clocks and eight brain age models predicted chronological age modestly, stabilizing by middle childhood; their age residuals were weakly associated.

Developing a multi-modal neuroimaging-based BrainAge model across childhood

This paper develops and benchmarks BrainAge models using multi-modal neuroimaging data from childhood cohorts to distinguish healthy from symptomatic developmental trajectories.

Microglial function moderates the relation between depression risk factors and depression outcomes across the life course in females

The paper shows that microglial function influences how depression risk factors affect depression outcomes differently in females compared to males across the life course.