Fangchen Zhu

A parallel channel of state-dependent sensory signaling from the cholinergic basal forebrain to the auditory cortex

This study shows that cholinergic basal forebrain axons send non-habituating, stimulus-specific sensory signals to the auditory cortex, independent of local tonotopy and modulated by slow cholinergic activity.

Application of Optogenetic Amyloid-β Distinguishes Between Metabolic and Physical Damage in Neurodegeneration

This study uses optogenetic Amyloid-β to distinguish between metabolic and physical damage in Alzheimer's disease, showing that oligomerization causes severe tissue loss and that Li+ treatment reduces lifespan deficits.