Author

Andrew S. Holston

University of OregonORCID 0000-0002-4918-1442Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein design· 2 Assay:proteomics· 1

Frequent Co-Authors

Calin PlesaiD· 2 shared Samuel R. HintoniD· 2 shared Karl J. RomanowicziD· 1 shared Kyra A. LindleyiD· 1 shared Lucas LippertiD· 1 shared Nora Kearns· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersSynthetic Biology

Calin PlesaORCID

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2 papers

Recent·Most cited

Synthetic BiologyACS Synthetic BiologyPeer-reviewedSep 23, 2026

Characterizing Sequence-Function Relationships in Chimeric DcuS/EnvZ Histidine Kinases at Scale

Lucas Lippert, Andrew S. Holston, Samuel R. Hinton…·Calin Plesa

The paper develops a synthetic system to screen chimeric DcuS/EnvZ histidine kinases and identifies key residues affecting ligand responsiveness and selectivity.

DOI 10.1021/acssynbio.6c00448

proteomicsexperimental assay

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Synthetic BiologybioRxivPreprintDec 11, 2023

Degenerate DropSynth for Simultaneous Assembly of Diverse Gene Libraries and Local Designed Mutants

Andrew S. Holston, Samuel R. Hinton, Kyra A. Lindley…·Calin Plesa

The paper introduces Degenerate DropSynth, a method for assembling diverse gene libraries and local mutants, demonstrating scalability and efficiency in protein engineering.

10 citations

experimental assayprotein design

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