Author

Patrick A. Williams

Children's Hospital of PhiladelphiaORCID 0000-0002-4919-9685Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Kathryn E. HamiltoniD· 2 shared Lauren A. Simon· 2 shared Ayano KondoiD· 1 shared Benjamin J. WilkinsiD· 1 shared Charles H. DananiD· 1 shared David A. Piccoli· 1 shared David S.M. Lee· 1 shared Emma T. Lundsmith· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Kathryn E. HamiltonORCID

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2 papers

Recent·Most cited

TNFSF13 insufficiency disrupts human colonic epithelial cell-mediated B cell differentiation

Xianghui Ma, Noor B. Dawany, Ayano Kondo, Kelly Maurer, Tatiana A. Karakasheva, Rawan Shraim, Patrick A. Williams, Louis R. Parham, Lauren A. Simon, Charles H. Danan, Máire A. Conrad, David A. Piccoli, Marcella Devoto, Kathleen E. Sullivan, Klaus H. Kaestner, , Kathryn E. Hamilton

This study investigates the role of TNFSF13 in colonic epithelial cell-B cell interactions and finds that TNFSF13 insufficiency disrupts B cell differentiation and epithelial growth.

bioRxiv · Sep 23, 2024 · PreprintMolecular Biology

Posttranscriptional regulation of intestinal epithelial cell repair by RNA binding protein IMP1

Priya Chatterji, Kelly A. Whelan, Sarah F. Andres, Fernando C. Samper, Lauren A. Simon, Rei Mizuno, Emma T. Lundsmith, David S.M. Lee, Shun Liang, H.R. Sagara Wijeratne, Stefanie Marti, Lillian Chau, Patrick A. Williams, Veronique Giroux, Benjamin J. Wilkins, , Kathryn E. Hamilton

This study shows IMP1 regulates intestinal epithelial repair after irradiation and colitis by modulating autophagy through direct binding to autophagy transcripts.

bioRxiv · Jul 12, 2018 · PreprintPhysiology