Author

Matt C. Demelo

Rice UniversityORCID 0000-0002-4929-4340Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:trajectory inference· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Ali Murtaza· 1 shared Arushi Singhai· 1 shared Catalina A. Dentzel Helmy· 1 shared Chang C. LiuiD· 1 shared Courtney K. CarlsoniD· 1 shared Guohao Liang· 1 shared Marcello Pajoh-Casco· 1 shared Michelle Ficht· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Ali Murtaza

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1 paper

Recent·Most cited

Open-ended molecular recording of sequential cellular events into DNA

Theresa B. Loveless, Courtney K. Carlson, Catalina A. Dentzel Helmy, Vincent J. Hu, Sara K. Ross, Matt C. Demelo, Ali Murtaza, Guohao Liang, Michelle Ficht, Arushi Singhai, Marcello Pajoh-Casco, Chang C. Liu

This paper introduces peCHYRON, a DNA recorder that sequentially records cellular events in mammalian cells using prime editing, enabling durable, high-information, and temporally resolved molecular recording.

Nature Chemical Biology · Nov 14, 2024Peer-reviewedGenetics