Author

Amy V. Kaucher

University of CopenhagenORCID 0000-0002-4929-4789Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Eva R. HoffmanniD· 2 shared Hannah R. SchorleiD· 2 shared Jason Alexander HalliwelliD· 2 shared Kathleen R. Stewart-MorganiD· 2 shared Ruiqi SuniD· 2 shared Anja Bisgaard PinborgiD· 1 shared Anna MurrayiD· 1 shared Bárbara ParreiraiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

Eva R. HoffmannORCID

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2 papers

Recent·Most cited

Loss of FANCM impairs primordial germ cell differentiation in vitro

Amy V. Kaucher, Hannah R. Schorle, Bárbara Parreira, Ruiqi Sun, Kathleen R. Stewart-Morgan, Anja Bisgaard Pinborg, Eva R. Hoffmann, Jason Alexander Halliwell

This study shows that FANCM loss in a mouse in vitro primordial germ cell model reduces PGCLC formation, indicating its critical role in early germline development.

bioRxiv · Feb 11, 2026 · PreprintCell Biology

PARP1 regulates establishment of the ovarian reserve and age at natural menopause

Hannah R. Schorle, Jason Alexander Halliwell, Jonas Damgaard Elsborg, Stasa Stankovic, Emily J Morbey, Jack R A Murzynowski, Amy V. Kaucher, Ruiqi Sun, Michael Lund Nielsen, Kathleen R. Stewart-Morgan, Anna Murray, Jesper Velgaard Olsen, John R. B. Perry, Eva R. Hoffmann

This study identifies a variant in PARP1 associated with earlier menopause by affecting primordial germ cell fate through altered DNA binding and transcriptional regulation.

medRxiv · Jun 18, 2025 · PreprintGenetic & Genomic Medicine