Jason Alexander Halliwell

The paper uses pulsed-SILAC in single mouse embryos to study protein synthesis dynamics and phosphosite regulation during early embryogenesis, revealing active maternal proteome synthesis and post-translational regulation.

This study shows that FANCM loss in a mouse in vitro primordial germ cell model reduces PGCLC formation, indicating its critical role in early germline development.

The paper maps H2A.Z incorporation during mouse oogenesis, identifying distinct patterns and their relationship with epigenetic marks and transposable elements.

This study identifies a variant in PARP1 associated with earlier menopause by affecting primordial germ cell fate through altered DNA binding and transcriptional regulation.

The paper investigates DNA replication timing in mouse zygotes and 2-cell embryos, revealing an asynchronous replication program in 2-cell embryos that differs from embryonic stem cells.