Author

Melinda Ann Brindley

University of GeorgiaORCID 0000-0002-4929-8085Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Ecology· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Angela LekiD· 1 shared Blanka TeslaiD· 1 shared Christine L. O’ConnoriD· 1 shared Courtney C. Murdock· 1 shared Courtney Cuinn MurdockiD· 1 shared Elvira Cynthia Alves HorácioiD· 1 shared Jiangxingzi XuiD· 1 shared John M. DrakeiD· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperGenetics

Angela LekORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Deep Mutational Scanning in Disease-related Genes with Saturation Mutagenesis-Reinforced Functional Assays (SMuRF)

Kaiyue Ma, Shushu Huang, Kenneth K.H. Ng, Nicole J. Lake, Soumya Joseph, Jiangxingzi Xu, Angela Lek, Lin Ge, Keryn G. Woodman, Katherine E. Koczwara, Justin Cohen, Vincent Ho, Christine L. O’Connor, Melinda Ann Brindley, Kevin P. Campbell, Monkol Lek

This paper introduces SMuRF, a framework for deep mutational scanning in disease-related genes, generating functional scores for all coding variants and aiding in variant interpretation.

bioRxiv · Jul 12, 2023 · PreprintGenetics

Temperature Dramatically Shapes Mosquito Gene Expression with Consequences for Mosquito-Zika Virus Interactions

Priscila Gonçalves Ferreira, Blanka Tesla, Elvira Cynthia Alves Horácio, Laila Alves Nahum, Melinda Ann Brindley, Tiago Antônio de Oliveira Mendes, Courtney Cuinn Murdock

This study examines how temperature affects mosquito gene expression and ZIKV infection outcomes by comparing transcriptomes at different temperatures.

Frontiers in Microbiology · Jun 12, 2020Peer-reviewedMolecular Biology

Carry-over effects of larval microclimate on the transmission potential of a mosquito-borne pathogen

Michelle V. Evans, Justine C. Shiau, Nicole Solano, Melinda A. Brindley, John M. Drake, Courtney C. Murdock

This study investigates how larval microclimate affects dengue transmission in Aedes albopictus by incorporating carry-over effects into a transmission model.

bioRxiv · Dec 1, 2017 · PreprintEcology