GeneticsGeneticsPeer-reviewed
Comprehensive scanning mutagenesis of human retrotransposon LINE-1 identifies motifs essential for function
Emily M. Adney, Matthias Thomas Ochmann, Srinjoy Sil…·Jef D. Boeke
The paper identifies functionally important regions in ORF1p and ORF2p of human LINE-1 through trialanine mutagenesis, showing most mutants lose retrotransposition activity.
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