Author

Denise Sighel

University of TrentoORCID 0000-0002-4950-7254Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Alessandro QuattroneiD· 2 shared Alessandro RomaneliD· 1 shared Alessia SoldanoiD· 1 shared Andrea CappanniniiD· 1 shared Chiara Maria ArgentoiD· 1 shared Davide DalfovoiD· 1 shared Eliana DestefanisiD· 1 shared Emanuele Filiberto RosattiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Alessandro QuattroneORCID

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2 papers

Recent·Most cited

Unveiling Oligodendrocyte-Lineage Differentiation in the Glioblastoma Infiltrative Zone Through Spatial Transcriptomics

Chiara Maria Argento, Enrico Sebastiani, Emanuele Filiberto Rosatti, Denise Sighel, Sara Longhi, Alessia Soldano, Toma Tebaldi, Alessandro Quattrone, Francesco Corsini, Luciano Annicchiarico, Mattia Barbareschi, Lorenza Pecciarini, Pietro Luigi Poliani

This study uses spatial transcriptomics to show that infiltrative glioblastoma cells differentiate toward an oligodendrocyte-like state, which may contribute to tumor invasion and recurrence.

bioRxiv · Oct 20, 2025 · PreprintCancer Biology

The three YTHDF paralogs and VIRMA are the major tumor drivers among the m6A core genes in a pan-cancer analysis

Eliana Destefanis, Denise Sighel, Davide Dalfovo, Riccardo Gilmozzi, Francesca Broso, Andrea Cappannini, Janusz Marek Bujnicki, Alessandro Romanel, Erik Dassi, Alessandro Quattrone

This study identifies YTHDF paralogs and VIRMA as major tumor drivers among m6A core genes through a pan-cancer analysis of 10,000 samples.

NAR Cancer · Oct 3, 2024Peer-reviewedCancer Biology