Author

Farzaneh Darbeheshti

Dana-Farber Cancer InstituteORCID 0000-0002-4957-9004Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:variant calling· 2 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Gerassimos Mike MakrigiorgosiD· 2 shared Hayet Radia ZeggariD· 2 shared Ruolin LiuiD· 2 shared Viktor A. AdalsteinssoniD· 2 shared Athina N. MarkouiD· 1 shared Azeet NarayaniD· 1 shared Eleni ThanouiD· 1 shared Evi S. LianidouiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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10 top collaborators · 40 mutual co-author links

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2 shared papersMolecular Biology

Gerassimos Mike MakrigiorgosORCID

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2 papers

Recent·Most cited

Molecular BiologyNucleic Acids ResearchPeer-reviewedJan 16, 2026

Genome-wide extraction of differentially methylated DNA regions using adapter-anchored proximity primers

Farzaneh Darbeheshti, Hayet Radia Zeggar, Hamzeh Salmani…·Gerassimos Mike Makrigiorgos

The paper introduces aMAPP, a PCR-based method to enrich methylated or unmethylated CpGs, enabling sensitive detection of DMRs in cancer samples with low DNA input.

DOI 10.1093/nar/gkag056

humanDNA methylation

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GenomicsNucleic Acids ResearchPeer-reviewedMay 21, 2025

Methyl-CODEC enables simultaneous methylation and duplex sequencing

Ruolin Liu, Farzaneh Darbeheshti, Laurel Walsh…·Viktor A. Adalsteinsson

Methyl-CODEC enables simultaneous methylation and duplex sequencing, improving mutation detection and distinguishing methylated Cs from mutations.

6 citations

DNA methylationwhole-genome sequencing

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