Optimizing twin prime editing components for scalable genome editing and therapy in spinocerebellar ataxia type 3
Lee Wha Gwon, Jung Bae Seong, Hyeon-Gu Yeo, Yeounsun Oh, Junghyung Park, Jinyoung Won, Sang Je Park, Younghyun Kim, Jae‐Won Huh, Aryun Kim, Kwang-Hyun Park, Seung Hwan Lee
This study optimizes twin prime editing components to improve genome editing efficiency and accuracy for therapeutic applications in spinocerebellar ataxia type 3.
Molecular Therapy — Nucleic Acids · Jun 17, 2026Peer-reviewedBioengineering