Author

Maryam Safari

Columbia University Irving Medical CenterORCID 0000-0002-4972-6780Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Agnès BassevilleiD· 1 shared Amy W. KuiD· 1 shared Christopher B. DamociiD· 1 shared Daniel RomoiD· 1 shared Diana V. MoralesiD· 1 shared Haoran XueiD· 1 shared Helen Elaine RemottiiD· 1 shared Kenneth G. HulliD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Agnès BassevilleORCID

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1 paper

Recent·Most cited

Combined HDAC and eIF4A inhibition: A novel epigenetic therapy for pancreatic adenocarcinoma

Maryam Safari, Luigi Scotto, Agnès Basseville, Thomas Litman, Haoran Xue, Lubov Petrukhin, Ping Zhou, Helen Elaine Remotti, Amy W. Ku, Diana V. Morales, Christopher B. Damoci, Mingzhao Zhu, Ravikanth Maddipati, Kenneth G. Hull, Robert W. Robey, , Susan Elaine Bates

This paper shows that combining HDAC and eIF4A inhibitors effectively treats pancreatic cancer by inducing epigenetic reprogramming and metabolic stress in preclinical models.

Drug Resistance Updates · Oct 5, 2025Peer-reviewedCancer Biology