Author

Thomas Litman

University of CopenhagenORCID 0000-0002-6068-901XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Aashiq Hussain MirzaiD· 1 shared Agnès BassevilleiD· 1 shared Amy W. KuiD· 1 shared Bartosz PileckiiD· 1 shared Cecilie Amalie Brøgger SvaneiD· 1 shared Christian AnthoniD· 1 shared Christopher B. DamociiD· 1 shared Claus Heiner Bang‐BerthelseniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMolecular Biology

Aashiq Hussain MirzaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Combined HDAC and eIF4A inhibition: A novel epigenetic therapy for pancreatic adenocarcinoma

Maryam Safari, Luigi Scotto, Agnès Basseville, Thomas Litman, Haoran Xue, Lubov Petrukhin, Ping Zhou, Helen Elaine Remotti, Amy W. Ku, Diana V. Morales, Christopher B. Damoci, Mingzhao Zhu, Ravikanth Maddipati, Kenneth G. Hull, Robert W. Robey, , Susan Elaine Bates

This paper shows that combining HDAC and eIF4A inhibitors effectively treats pancreatic cancer by inducing epigenetic reprogramming and metabolic stress in preclinical models.

Drug Resistance Updates · Oct 5, 2025Peer-reviewedCancer Biology

Transcriptome profiling of ulcerative colitis mouse model suggests biomarkers and therapeutic targets for human colitis

Reza Yarani, Oana Palasca, Nadezhda T. Doncheva, Christian Anthon, Bartosz Pilecki, Cecilie Amalie Brøgger Svane, Aashiq Hussain Mirza, Thomas Litman, Uffe Holmskov, Claus Heiner Bang‐Berthelsen, MOGENS VILIEN, Lars Juhl Jensen, Jan Gorodkin, Flemming Pociot

The paper identifies 51 differentially regulated genes in UC colon and blood by comparing a DSS-UC mouse model with human UC data, suggesting biomarkers and therapeutic targets.

bioRxiv · Aug 12, 2020 · PreprintMolecular Biology