PhysiologybioRxivPreprint
Bacterial Peptidoglycan Extends Lifespan by Activating Lysosomal Activity through V-ATPase Binding
Herui Fu, Jia Tie, Yan Zhou…·Bin Qi
This study identifies bacterial peptidoglycan as a conserved activator of lysosomal function that extends lifespan in C. elegans and mice by enhancing V-ATPase activity and lysosomal acidification.
DOI 10.64898/2026.08.28.747948