ImmunologybioRxivPreprint
Extracellular ISG15 triggers ISGylation via a type-I interferon independent non-canonical mechanism to regulate host response during virus infection
Lindsay Grace Miller, Kim Lam Chiok, Charles Mariasoosai…·Santanu Bose
This study identifies extracellular ISG15 as a soluble antiviral factor that promotes IFN-independent ISGylation through integrin-FAK pathway activation during virus infection.
3 citations