Santanu Bose

Structural insights into the molecular recognition of integrin αVβ3 by RGD-containing ligands: The role of the specificity-determining loop (SDL)

This study analyzes the molecular interactions and structural changes of integrin αVβ3's ligand-binding domain to identify key residues and allosteric mechanisms involved in ligand recognition and regulation.

Extracellular ISG15 triggers ISGylation via a type-I interferon independent non-canonical mechanism to regulate host response during virus infection

This study identifies extracellular ISG15 as a soluble antiviral factor that promotes IFN-independent ISGylation through integrin-FAK pathway activation during virus infection.