Author

Michael N. Teng

University of South FloridaORCID 0000-0002-0722-3659Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1 Assay:proteomics· 1

Frequent Co-Authors

Angelo A. NicolaciiD· 1 shared Annette A. MachadoiD· 1 shared Arthur L. Haas· 1 shared Charles MariasoosaiiD· 1 shared Do-Kyun KimiD· 1 shared Felipe-Andrés PiedraiD· 1 shared Indira P. Mohanty· 1 shared Jameela LokhandwalaiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMolecular Biology

Angelo A. NicolaciORCID

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Author profile →

3 papers

Recent·Most cited

Targeted degradation of the HPV oncoprotein E6 reduces tumor burden in cervical cancer

Tracess B. Smalley, Angelo A. Nicolaci, Kim C. Tran, Jameela Lokhandwala, Nina Obertopp, Jenet K. Matlack, Robert E Miner, Michael N. Teng, Shari Pilon‐Thomas, Jennifer M. Binning

This study develops a PROTAC that degrades HPV E6 protein, reducing tumor burden in a mouse model and showing immune dependence.

Molecular Therapy · Aug 26, 2025Peer-reviewedMolecular Biology

Extracellular ISG15 triggers ISGylation via a type-I interferon independent non-canonical mechanism to regulate host response during virus infection

Lindsay Grace Miller, Kim Lam Chiok, Charles Mariasoosai, Indira P. Mohanty, Sudiksha Pandit, Pallavi Deol, Liyon Mehari, Michael N. Teng, Arthur L. Haas, Senthil Natesan, Tanya A. Miura, Santanu Bose

This study identifies extracellular ISG15 as a soluble antiviral factor that promotes IFN-independent ISGylation through integrin-FAK pathway activation during virus infection.

bioRxiv · Jul 5, 2024 · PreprintImmunology

Genotype-dependent and non-gradient patterns of RSV gene expression

Felipe-Andrés Piedra, Xueting Qiu, Michael N. Teng, Vasanthi Avadhanula, Annette A. Machado, Do-Kyun Kim, James E. Hixson, Justin Bahl, Pedro A. Piedra

This study shows RSV gene expression is genotype-dependent and non-gradient, with the G gene consistently more expressed than upstream genes, suggesting a novel transcriptional regulation mechanism involving GS signal N-phase alignment.

PLoS ONE · Jan 10, 2020Peer-reviewedMolecular Biology