Cancer BiologybioRxivPreprint
Targeting the FBXL12-FANCD2 Pathway Disrupts Replication Stress Tolerance in MYCN-Driven Neuroblastoma
Jinjiang Chou, Alena Malyukova, Alessandro Simone Bordonaro…·Olle Sangfelt
This study identifies the FBXL12-FANCD2 pathway as a vulnerability in MYCN-driven neuroblastoma, showing its role in replication stress tolerance and potential as a therapeutic target.
DOI 10.64898/2026.08.29.745966