Author

Vikram Dalal

Washington University in St. LouisORCID 0000-0002-5000-8903Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Approach:mixed model· 1 Assay:protein structure· 1

Frequent Co-Authors

Wayland W.L. ChengiD· 3 shared Brandon K. TaniD· 1 shared David FaniD· 1 shared Erik R. LindahliD· 1 shared Fong‐Fu HsuiD· 1 shared Hanrui XuiD· 1 shared Kirby T. MorelandiD· 1 shared Mark J. ArcarioiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiophysics

Wayland W.L. ChengORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular determinants of ligand recognition and efficacy in the TRPM3 voltage sensor-like domain

Vikram Dalal, Vipin Ashok Rangari, Samuel Eriksson Lidbrink, Kirby T. Moreland, Erik R. Lindahl, Rebecca J. Howard, Susruta Majumdar, Wayland W.L. Cheng

This study identifies molecular determinants of ligand recognition and efficacy in TRPM3's voltage sensor-like domain using a combination of structural and functional analyses.

bioRxiv · Sep 30, 2026 · PreprintBiophysics

Thermotropic Properties of Large, Circularized Nanodiscs

Mark J. Arcario, Vikram Dalal, David Fan, Fong‐Fu Hsu, Wayland W.L. Cheng

This study examines how the size of circularized nanodiscs affects lipid bilayer properties, finding that larger nanodiscs better approximate lipid behavior in large unilamellar vesicles.

Biochimica et Biophysica Acta (BBA) - Biomembranes · Sep 12, 2025Peer-reviewedBiophysics

Cryo-EM structures of a pentameric ligand-gated ion channel in liposomes

Vikram Dalal, Brandon K. Tan, Hanrui Xu, Wayland W.L. Cheng

This study determines the cryo-EM structures of ELIC in liposomes, revealing the desensitization gate and showing that liposomes better capture functional states than nanodiscs.

eLife · Jul 16, 2025Peer-reviewedBiophysics