Author

Tatsiana Aneichyk

Broad InstituteORCID 0000-0002-5002-3695Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1

Frequent Co-Authors

Alexei StortchevoiiD· 2 shared Ashok RagavendraniD· 2 shared Benjamin CurralliD· 2 shared Dadi GaoiD· 2 shared Michael E. TalkowskiiD· 2 shared Rachita YadaviD· 2 shared Ryan L. CollinsiD· 2 shared Alex R. HastieiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersGenomics

Alexei StortchevoiORCID

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3 papers

Recent·Most cited

Tissue and cell-type specific molecular and functional signatures of 16p11.2 reciprocal genomic disorder across mouse brain and human neuronal models

Derek J.C. Tai, Parisa Razaz, Serkan Erdin, Dadi Gao, Jennifer P Wang, Xander Nuttle, Celine E. de Esch, Ryan L. Collins, Benjamin Currall, Kathryn O’Keefe, Nicholas D. Burt, Rachita Yadav, Lily Wang, Kiana Mohajeri, Tatsiana Aneichyk, , James F. Gusella

This study identifies molecular and functional changes in mouse and human models of 16p11.2 reciprocal genomic disorder, revealing context-specific disruptions in energy metabolism, RNA processing, and neuronal development.

The American Journal of Human Genetics · Sep 23, 2022Peer-reviewedGenomics

Comprehensive evaluation of computational cell-type quantification methods for immuno-oncology

Gregor Sturm, Francesca Finotello, Florent Petitprez, Jitao David Zhang, Jan Baumbach, Wolf H. Fridman, Markus List, Tatsiana Aneichyk

The paper evaluates computational methods for estimating immune-cell composition from bulk RNA-seq data using simulated and real datasets, finding high accuracy for well-defined cell-type signatures.

Bioinformatics · May 9, 2019Peer-reviewedBioinformatics

Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly

Tatsiana Aneichyk, William T. J. Hendriks, Rachita Yadav, David S. Shin, Dadi Gao, Christine A. Vaine, Ryan L. Collins, Aloysius Domingo, Benjamin Currall, Alexei Stortchevoi, Trisha Multhaupt‐Buell, Ellen B. Penney, Lilian Cruz, Jyotsna Dhakal, Harrison Brand, , Michael E. Talkowski

This study identifies the causal mechanism of X-linked Dystonia-Parkinsonism (XDP) by integrating genome and transcriptome assembly, revealing a SVA insertion causing intron retention and TAF1 dysfunction.

Cell · Jan 1, 2018Peer-reviewedGenomics