Felicity C. Jones

This study shows that epigenetic priming of healthy donor CD34+ stem cells drives S100A8/A9-driven inflammation, enhancing NK cell anti-leukemic activity during hematopoietic differentiation and improving response to 5-AzaC therapy in MDS.

The paper shows that freshwater threespine stickleback fish have evolved expanded copies of the MYH3C gene family, which is linked to muscle development and adaptive divergence from marine populations.

This study introduces ReMIX, a method to detect meiotic crossovers in single individuals using linked-read sequencing, achieving high-resolution recombination maps in mice and stickleback.

This study shows cis-regulatory changes predominantly drive gene expression divergence in sticklebacks, with parallel expression patterns linked to adaptive genomic regions and natural selection.