Elena Avdievich

This paper develops a CRISPR-Cas method for gene knock-out and endogenous protein tagging in the brown alga Ectocarpus, enhancing functional genomics capabilities.

The paper presents a lineage-wide evolutionary analysis of 3D genome architecture and organization across brown algae, revealing conserved chromosomal features, lineage-specific rearrangements, and long-term co-evolution of centromeres and retrotransposons.

The paper analyzes brown algal genomes to trace the origin and evolution of U/V sex chromosomes, revealing gene gain-driven evolution and the demise of these systems through hermaphroditism and gene hierarchy shifts.

The paper maps the 3D chromatin structure of sex chromosomes in the brown alga Ectocarpus, revealing their spatial organization and links to gene expression and sex determination.

This study introduces ReMIX, a method to detect meiotic crossovers in single individuals using linked-read sequencing, achieving high-resolution recombination maps in mice and stickleback.