Author

Rémy Tuyéras

Broad InstituteORCID 0000-0002-5032-4113Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Leandro Z. AgudeloiD· 3 shared M KellisiD· 3 shared Álvaro MorcuendeiD· 2 shared Burak KutluiD· 2 shared Claudia Llinares· 2 shared Kevin L. GroveiD· 2 shared Teresa FemeníaiD· 2 shared Anjanet R. Loon· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersSystems Biology

Leandro Z. AgudeloORCID

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3 papers

Recent·Most cited

Rectifying Stress into Structural Memory Drives Specialization in Cells and Adaptive Computational Systems

Rémy Tuyéras, Álvaro Morcuende, Claudia Llinares, Åsa Segerstolpe, M Kellis, Teresa Femenía, Leandro Z. Agudelo

This paper identifies asymmetric-drive rectification as a mechanism converting stress into structural memory, enabling functional specialization in cells and adaptive computational systems.

bioRxiv · Feb 1, 2026 · PreprintBiophysics

Cellular intelligence: dynamic specialization through non-equilibrium multi-scale compartmentalization

Rémy Tuyéras, Leandro Z. Agudelo, Soumya P. Ram, Anjanet R. Loon, Burak Kutlu, Kevin L. Grove, M Kellis

This paper introduces a framework using operads to model cellular intelligence through non-equilibrium compartmentalization and applies it as an unsupervised learning algorithm to machine learning datasets.

bioRxiv · Jun 25, 2021 · PreprintSystems Biology

Metabolic resilience is encoded in genome plasticity

Leandro Z. Agudelo, Rémy Tuyéras, Claudia Llinares, Álvaro Morcuende, Yongjin Park, Na Sun, Suvi Linna-Kuosmanen, Naeimeh Atabaki‐Pasdar, Li‐Lun Ho, Kyriaki Galani, Paul W. Franks, Burak Kutlu, Kevin L. Grove, Teresa Femenía, M Kellis

The paper investigates how genome plasticity and transcriptional organization enable metabolic resilience to nutrient limitation and fasting endurance.

bioRxiv · Jun 25, 2021 · PreprintSystems Biology