Author

Anjanet R. Loon

Massachusetts Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Li‐Huei TsaiiD· 3 shared M KellisiD· 2 shared Oyku CeritiD· 2 shared Abigail K. R. Lytton‐JeaniD· 1 shared Adele Bubnys· 1 shared Alan Y. L. JiangiD· 1 shared Alexander Seguin· 1 shared Alexis Davison· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Li‐Huei TsaiORCID

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Author profile →

4 papers

Recent·Most cited

Engineered 3D Immuno-Glial-Neurovascular Human miBrain Model

Alice E. Stanton, Adele Bubnys, Emre Agbas, Benjamin T. James, Dong Shin Park, Alan Y. L. Jiang, Rebecca L. Pinals, Liwang Liu, Nhat Truong, Anjanet R. Loon, Colin Staab, Oyku Cerit, Hsin-Lan Wen, David V. Mankus, Margaret E. Bisher, , Li‐Huei Tsai

The paper constructs a 3D human brain model integrating multiple cell types to study Alzheimer's Disease mechanisms linked to APOE4.

Proceedings of the National Academy of Sciences · Oct 17, 2025Peer-reviewedNeuroscience

The role of cholinergic signaling in multi-sensory gamma stimulation induced perivascular clearance of amyloid

Nicolas Lavoie, Cristina Blanco‐Duque, Martin C. Kahn, Hiba Nawaid, Anjanet R. Loon, Alexander Seguin, Ravikiran M. Raju, Alexis Davison, Cheng-Yi Yang, Li‐Huei Tsai

This study shows that cholinergic signaling is crucial for GENUS-induced perivascular amyloid clearance in Alzheimer's mouse models.

bioRxiv · Nov 27, 2024 · PreprintNeuroscience

Distinct effects of disease-associated TREM2 R47H/+ and T66M mutations on iPSC-derived microglia.

Jay Penney, William T. Ralvenius, Anjanet R. Loon, Oyku Cerit, Vishnu Dileep, Blerta Milo, Hannah Woolf, Li‐Huei Tsai

This study compares the effects of TREM2 R47H/+ and T66M mutations on iPSC-derived microglia, finding distinct gene expression and functional changes linked to neurodegeneration.

bioRxiv · Oct 5, 2022 · PreprintNeuroscience

Cellular intelligence: dynamic specialization through non-equilibrium multi-scale compartmentalization

Rémy Tuyéras, Leandro Z. Agudelo, Soumya P. Ram, Anjanet R. Loon, Burak Kutlu, Kevin L. Grove, M Kellis

This paper introduces a framework using operads to model cellular intelligence through non-equilibrium compartmentalization and applies it as an unsupervised learning algorithm to machine learning datasets.

bioRxiv · Jun 25, 2021 · PreprintSystems Biology