Author

Frédéric Fontaine

Austrian Academy of SciencesORCID 0000-0002-5044-1029Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:metabolomics· 2 Assay:proteomics· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

André C. MülleriD· 2 shared Antoni Gañez ZapateriD· 2 shared Lorena EspinariD· 2 shared Sara SdelciiD· 2 shared Savvas KourtisiD· 2 shared Albert Coll‐Manzano· 1 shared Alfredo SmirigliaiD· 1 shared Amandine MorettoniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

André C. MüllerORCID

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2 papers

Recent·Most cited

Nuclear metabolism oscillation during the cell cycle reveals a link between the phosphatidylinositol pathway and histone methylation.

Antoni Gañez Zapater, Savvas Kourtis, Camilla Reiter Elbæk, Lorena Espinar, Carolina Toro‐Márquez, Albert Coll‐Manzano, Alfredo Smiriglia, Laura García‐López, Laura Wiegand, María Guirola, Frédéric Fontaine, Andrea Morandi, André C. Müller, Sara Sdelci

This study identifies cell cycle-dependent nuclear phosphatidylinositol metabolism and its impact on histone methylation and heterochromatin states.

Advanced Science · Apr 21, 2026Peer-reviewedCell Biology

A metabolic map of the DNA damage response identifies PRDX1 in nuclear ROS scavenging and aspartate synthesis

Amandine Moretton, Savvas Kourtis, Antoni Gañez Zapater, Chiara Calabrò, Lorena Espinar, Frédéric Fontaine, Evangelia Darai, Etna Abad, Samuel Block, Laura Pascual‐Reguant, Natalia Pardo Lorente, Ritobrata Ghose, Matthew G. Vander Heiden, Ana Janic, André C. Müller, , Sara Sdelci

The paper identifies PRDX1 as essential for DNA damage repair by scavenging nuclear ROS and regulating aspartate synthesis during the DNA damage response.

Molecular Systems Biology · Jun 1, 2023Peer-reviewedMolecular Biology