Molecular BiologybioRxivPreprint
DNA damage-induced interaction between a lineage addiction oncogenic transcription factor and the MRN complex shapes a tissue-specific DNA Damage Response and cancer predisposition
Romuald Binet, Jean‐Philippe Lambert, Markéta Tomková…·Colin R. Goding
This study shows that the transcription factor MITF interacts with the MRN complex to modulate the DNA damage response in melanoma, contributing to cancer predisposition.
3 citations