Author

Toshinori Hinoue

Van Andel InstituteORCID 0000-0002-5078-5016Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:DNA methylation· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Peter W. LairdiD· 3 shared Hui SheniD· 2 shared Nathan J. SpixiD· 2 shared Wanding ZhouiD· 2 shared Alexandra VanderArk· 1 shared Andrew D. CherniackiD· 1 shared Andrew J Mungall· 1 shared Andy Chu· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersGenomics

Peter W. LairdORCID

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3 papers

Recent·Most cited

GenomicsNature CommunicationsPeer-reviewedJul 7, 2025

High-coverage allele-resolved single-cell DNA methylation profiling by scDEEP-mC reveals cell lineage, X-inactivation state, and replication dynamics

Nathan J. Spix, Walid Abi Habib, Zhouwei Zhang…·Peter W. Laird

The paper introduces scDEEP-mC, a single-cell DNA methylation profiling method, and shows it can identify cell types, X-inactivation states, and replication dynamics with high coverage.

9 citations

humanDNA methylation

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GenomicsCell GenomicsPeer-reviewedJul 1, 2022

DNA Methylation Dynamics and Dysregulation Delineated by High-Throughput Profiling in the Mouse

Wanding Zhou, Toshinori Hinoue, Bret Barnes…·Peter W. Laird

This paper develops a high-throughput DNA methylation array and atlas for mice, revealing tissue-specific methylation patterns and their associations with aging, differentiation, and disease.

120 citationstop 1%

mouseDNA methylation

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BioinformaticsCancer GeneticsPeer-reviewedJun 6, 2017

Comprehensive characterization of genomic, transcriptomic and epigenomic artifacts introduced in formalin-fixed, paraffin-embedded tissues.

Erik J. Zmuda, Kyle R Covington, Cyriac Kandoth…·Katherine A Hoadley

This study characterizes genomic, transcriptomic, and epigenomic artifacts in FFPE tissues and provides best practices to mitigate their impact on molecular analysis.

DOI 10.1016/j.cancergen.2017.04.029

humanwhole-exome sequencing

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