Author

Balamurali Krishna Ambati

Loma Linda University Medical CenterORCID 0000-0002-5087-1918Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Bonnie J. Archer· 2 shared Hironori UeharaiD· 2 shared Jayakrishna AmbatiiD· 2 shared Lara S. CarrolliD· 2 shared Xiaohui ZhangiD· 2 shared Albert S. JuniD· 1 shared Austin D. BohneriD· 1 shared Derick G. Holt· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersGenomics

Bonnie J. Archer

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2 papers

Recent·Most cited

GenomicseLifePeer-reviewedJun 8, 2021

Start codon disruption with CRISPR/Cas9 prevents murine Fuchs' endothelial corneal dystrophy

Hironori Uehara, Xiaohui Zhang, Felipe Pereira…·Balamurali Krishna Ambati

This study shows that CRISPR/Cas9 gene editing in adult mice prevents vision loss in a model of Fuchs' endothelial corneal dystrophy by disrupting the start codon of the mutant COL8A2 gene.

66 citations

mouseexperimental assay

Developmental BiologybioRxivPreprintFeb 21, 2020

Loss of Corneal Raver2 Expression in Aniridia Associated Keratopathy

Subrata Kumar Das, Lara S. Carroll, Derick G. Holt…·Balamurali Krishna Ambati

This study identifies Raver2 as a downstream factor of Pax6 in corneal development, showing its downregulation in aniridia-associated keratopathy in mice and humans.

DOI 10.1101/2020.02.21.959585

mousehuman