Jayakrishna Ambati

This study shows that male sex-specific anti-angiogenic effects of hIgG1 depend on the Y chromosome-encoded DDX3Y gene, revealing a mechanism for sex differences in AMD.

The paper evaluates the specificity of commercial antibodies targeting Y chromosome-encoded genes and finds many lack proper validation data.

This paper evaluates the learning curve for subretinal injection in mice among ophthalmic surgeons, finding a significant improvement in success rate after 364 training cases.

This study shows that CRISPR/Cas9 gene editing in adult mice prevents vision loss in a model of Fuchs' endothelial corneal dystrophy by disrupting the start codon of the mutant COL8A2 gene.

This study identifies Raver2 as a downstream factor of Pax6 in corneal development, showing its downregulation in aniridia-associated keratopathy in mice and humans.