GenomicseLifePeer-reviewed
Start codon disruption with CRISPR/Cas9 prevents murine Fuchs' endothelial corneal dystrophy
Hironori Uehara, Xiaohui Zhang, Felipe Pereira…·Balamurali Krishna Ambati
This study shows that CRISPR/Cas9 gene editing in adult mice prevents vision loss in a model of Fuchs' endothelial corneal dystrophy by disrupting the start codon of the mutant COL8A2 gene.
66 citations