Non-human primate LIBRA-Seq accelerates neutralizing antibody discovery in RM vaccinated against HIV-1
Christopher T. Edwards, Aaron D. Silva Trenkle, Anusmita Sahoo, Kendra Cruickshank, Sydney Nelson, Stacey A. Lapp, Nagarajan Raju, Thang Ton, Amanda Metz, Emily McGhee, Faith A. Mbadugha, Tysheena P. Charles, Ankur Saini, Kiran Gill, Kathryn L. Pellegrini, , Steven E. Bosinger
This paper develops a high-throughput method to identify and characterize neutralizing antibodies in vaccinated rhesus macaques, revealing key features of effective antibody responses.
PLoS Pathogens · Jul 28, 2026Peer-reviewedImmunology