Author

Tysheena P. Charles

Emory University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Cynthia A. DerdeyniD· 2 shared Aaron D. Silva TrenkleiD· 1 shared Alejandra ValdiviaiD· 1 shared Amanda MetziD· 1 shared Amit A. UpadhyayiD· 1 shared Ankur Saini· 1 shared Anusmita SahooiD· 1 shared Bernard P LassegueiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

Cynthia A. DerdeynORCID

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Author profile →

2 papers

Recent·Most cited

Non-human primate LIBRA-Seq accelerates neutralizing antibody discovery in RM vaccinated against HIV-1

Christopher T. Edwards, Aaron D. Silva Trenkle, Anusmita Sahoo, Kendra Cruickshank, Sydney Nelson, Stacey A. Lapp, Nagarajan Raju, Thang Ton, Amanda Metz, Emily McGhee, Faith A. Mbadugha, Tysheena P. Charles, Ankur Saini, Kiran Gill, Kathryn L. Pellegrini, , Steven E. Bosinger

This paper develops a high-throughput method to identify and characterize neutralizing antibodies in vaccinated rhesus macaques, revealing key features of effective antibody responses.

PLoS Pathogens · Jul 28, 2026Peer-reviewedImmunology

Poldip2 deficiency attenuates disease severity in a mouse model of COVID-19

Ruinan Hu, Alejandra Valdivia, Taylor E. White, Willy Ju, Maegan L. Brockman, Zhan Zhang, Hongyan Qu, Georgette M. Gafford, Giji Joseph, Samantha Burton, Leda Bassit, Tysheena P. Charles, Rebecca D. Levit, Cynthia A. Derdeyn, Kathy K. Griendling, , Marina S. Hernandes

This study shows that Poldip2 deficiency reduces lung inflammation and tissue damage in a mouse model of SARS-CoV-2 infection without affecting viral susceptibility.

bioRxiv · Jun 17, 2025 · PreprintPathology