Andrew W. Singson

Sperm activation for fertilization requires robust activity of the TAT-5 lipid flippase

This study shows that TAT-5 lipid flippase is essential for oocyte formation and sperm activation, with loss of TAT-5 reducing fertility and sperm activation.

The Caenorhabditis elegans spe-21 gene that encodes a palmitoyltransferase is necessary for spermiogenesis.

This study identifies spe-21 as a palmitoyltransferase essential for spermatid activation and spermatozoon formation in C. elegans.

The EGF-motif containing protein SPE-36 is a secreted protein required for sperm function at fertilization in C. elegans

This paper identifies SPE-36, a secreted EGF-motif protein in C. elegans, as essential for sperm function during fertilization despite normal morphology and behavior.

SPE-51, a sperm secreted protein with an Immunoglobulin-like domain, is required for sperm-egg fusion in C. elegans

The paper identifies SPE-51, a secreted protein in C. elegans, essential for sperm-egg fusion, and shows it localizes to the sperm surface.

spe-43 is required for sperm activation in C. elegans

This study identifies spe-43 as a gene required for spermiogenesis in C. elegans, showing that it is necessary for sperm activation in hermaphrodites but not in males.