Barth D. Grant

This study identifies SCM-1/SCAMP as a key factor maintaining microdomain boundaries in the endosomal system, ensuring proper cargo sorting and preventing microdomain overlap.

This study identifies PIKI-1 as a Class II PI3K essential for PI(3,4)P2 production and early endosomal function in C. elegans, showing its role in suppressing NEKL-related molting defects.

The paper shows that mechanical uterine distention enhances exopher extrusion from proteostressed C. elegans neurons, linking mechanical force to extracellular vesicle production and neurodegenerative disease mechanisms.

The paper investigates the fate of exophers in C. elegans, showing they are engulfed and degraded by hypodermal cells through a phagocytic process involving specific molecular factors.

The paper identifies SPE-51, a secreted protein in C. elegans, essential for sperm-egg fusion, and shows it localizes to the sperm surface.

This study identifies the catp-8/P5A-ATPase as a regulator of neuronal patterning in C. elegans, showing its role in dendrite morphogenesis, axon guidance, and neuronal migration through multiple genetic pathways.