Author

Simon Geoffrey Lillico

Roslin InstituteORCID 0000-0002-5101-2277Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:non-human primate· 1 Organism:plant (other)· 1

Frequent Co-Authors

Anna WargeliusiD· 1 shared Anne Hege Straume· 1 shared BRENDAN M. CORCORANiD· 1 shared Bruce WhitelawiD· 1 shared Christopher Proudfoot· 1 shared Erik Kjærner‐SembiD· 1 shared Greg Robert MarkbyiD· 1 shared Hilal GüralpiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Anna WargeliusORCID

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2 papers

Recent·Most cited

A refinement to gene editing in Atlantic salmon using asymmetrical oligonucleotide donors

Anne Hege Straume, Erik Kjærner‐Semb, Kai Ove Skaftnesmo, Hilal Güralp, Simon Geoffrey Lillico, Anna Wargelius, Rolf B. Edvardsen

This paper refines gene editing in Atlantic salmon using asymmetrical oligonucleotide donors, achieving efficient and precise genome modifications with up to 59.2% single nucleotide replacement efficiency.

bioRxiv · Feb 8, 2021 · PreprintMolecular Biology

Severe perinatal hydrops fetalis in genome edited pigs with a biallelic five base pair deletion of the Marfan syndrome gene, FBN1

Hiu‐Gwen Tsang, Simon Geoffrey Lillico, Christopher Proudfoot, Mary E. B. McCulloch, Greg Robert Markby, Violeta Trejo-Reveles, BRENDAN M. CORCORAN, Bruce Whitelaw, Vicky Elizabeth MacRae, KIM M. SUMMERS

This paper reports unexpected severe hydrops fetalis in CRISPR-Cas9 edited pigs with a FBN1 deletion, highlighting potential off-target effects and the need for comprehensive genomic analysis.

bioRxiv · Jul 20, 2020 · PreprintMolecular Biology