Author

Hiu‐Gwen Tsang

Roslin InstituteORCID 0000-0002-3353-6341Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:bulk RNA-seq· 2 Research Focus:database / resource· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Organism:plant (other)· 1

Frequent Co-Authors

KIM M. SUMMERSiD· 3 shared BRENDAN M. CORCORANiD· 2 shared Bruce WhitelawiD· 2 shared David Arthur HumeiD· 2 shared Emily L. ClarkiD· 2 shared Greg Robert MarkbyiD· 2 shared Mary E. B. McCullochiD· 2 shared Stephen J. BushiD· 2 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersGenomics

KIM M. SUMMERSORCID

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3 papers

Recent·Most cited

Severe perinatal hydrops fetalis in genome edited pigs with a biallelic five base pair deletion of the Marfan syndrome gene, FBN1

Hiu‐Gwen Tsang, Simon Geoffrey Lillico, Christopher Proudfoot, Mary E. B. McCulloch, Greg Robert Markby, Violeta Trejo-Reveles, BRENDAN M. CORCORAN, Bruce Whitelaw, Vicky Elizabeth MacRae, KIM M. SUMMERS

This paper reports unexpected severe hydrops fetalis in CRISPR-Cas9 edited pigs with a FBN1 deletion, highlighting potential off-target effects and the need for comprehensive genomic analysis.

bioRxiv · Jul 20, 2020 · PreprintMolecular Biology

Gene expression in the cardiovascular system of the domestic sheep (Ovis aries); a new tool to advance our understanding of cardiovascular disease.

Hiu‐Gwen Tsang, Emily L. Clark, Greg Robert Markby, Stephen J. Bush, David Arthur Hume, BRENDAN M. CORCORAN, Vicky Elizabeth MacRae, KIM M. SUMMERS

This study investigates gene expression in sheep cardiovascular tissues to understand vascular calcification, highlighting gene balance and extracellular matrix roles.

bioRxiv · Apr 24, 2020 · PreprintGenomics

A High Resolution Atlas Of Gene Expression In The Domestic Sheep (Ovis aries)

Emily L. Clark, Stephen J. Bush, Mary E. B. McCulloch, Iseabail Farquhar, Rachel A Young, Lucas Lefèvre, Clare Pridans, Hiu‐Gwen Tsang, Chunlei Wu, Cyrus Afrasiabi, Mick Watson, Bruce Whitelaw, Tom C. Freeman, KIM M. SUMMERS, Alan L. Archibald, David Arthur Hume

This paper presents a high-resolution gene expression atlas for sheep, identifying transcriptional signatures and functional annotations across tissues and developmental stages.

PLoS Genetics · Sep 15, 2017Peer-reviewedGenomics