David E. Greenberg

This paper introduces ORBIT, an oligonucleotide-based genetic toolkit for Pseudomonas aeruginosa that enables rapid, precise, and high-throughput hypomorph screening of essential genes.

The paper analyzes WGS data of E. coli isolates to show that blaTEM gene amplification correlates with resistance to AMC and TZP but not SAM, highlighting the need for comprehensive analysis of genetic determinants in BL/BLI resistance.

This study identifies non-carbapenemase-producing CRE mechanisms in recurrent Enterobacterales infections driven by porin loss and β-lactamase gene amplification.

VAMPr predicts antibiotic resistance using genomic data by analyzing variant associations and building machine learning models.