Author

Lyuba Varticovski

National Institutes of HealthORCID 0000-0002-5105-9008Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Gordon L. HageriD· 2 shared Agustina L. LafuenteiD· 1 shared Alba Jiménez‐PanizoiD· 1 shared Andrea Alegre‐MartíiD· 1 shared Annabel F. ValledoriD· 1 shared Deborah P. MerkeiD· 1 shared Diana A. StavrevaiD· 1 shared Diego M. PresmaniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenetics

Gordon L. HagerORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintDec 13, 2025

A Novel Patient-Derived Mutation in Glucocorticoid Receptor Reveals an Essential Role for DNA binding in Development and Endocrine Regulation

Theophilus T. Tettey, Qizong Lao, Sonal Vaid…·Gordon L. Hager

The paper identifies a novel GR mutation causing partial glucocorticoid resistance and shows its impact on development and endocrine regulation through patient-derived cells and a knock-in mouse model.

DOI 10.64898/2025.12.12.693739

humanexperimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMay 13, 2025

Bile acids target an exposed cavity in the glucocorticoid receptor modulating receptor self-assembly, chromatin binding and transcriptional activity

Alba Jiménez‐Panizo, Thomas A. Johnson, Kaustubh Wagh…·Eva Estébanez‐Perpiñá

This study shows bile acids bind to an exposed cavity on the glucocorticoid receptor, affecting its self-assembly and transcriptional activity.

3 citations

humanprotein structure

𝕏 PostBluesky