Kaustubh Wagh

QuantiTrack, a MATLAB GUI, unifies single-molecule detection, tracking, quality control and mobility analyses; for glucocorticoid receptor, hormone washout cut bound fraction, dwell times and low-mobility occupancy.

This study shows bile acids bind to an exposed cavity on the glucocorticoid receptor, affecting its self-assembly and transcriptional activity.

The paper identifies LxxLL motifs in NIPBL that regulate its interaction with MAU2 and steroid receptors, forming a ternary complex with GR to facilitate enhancer localization of cohesin.

This study shows that GR co-expression enhances MR transcriptional activity in response to aldosterone, even without glucocorticoids.