Author

S. Kashif Sadiq

European Molecular Biology LaboratoryORCID 0000-0002-5112-0307Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alessio Ling Jie YangiD· 1 shared Andreas MeyerhansiD· 1 shared Athanasios TypasiD· 1 shared Carine TisnéiD· 1 shared Carlos Geert Pieter VoogdtiD· 1 shared Cecilia Perez-BorrajeroiD· 1 shared Cristina Lorca-OróiD· 1 shared Elisabetta CacaceiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Alessio Ling Jie YangORCID

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2 papers

Recent·Most cited

BioinformaticsMolecular Systems BiologyPeer-reviewedJun 17, 2025

AlphaDesign: A de novo protein design framework based on AlphaFold

Michael Jendrusch, Alessio Ling Jie Yang, Elisabetta Cacace…·S. Kashif Sadiq

AlphaDesign uses AlphaFold to design novel protein structures, including monomers, dimers, and higher-order complexes, showing structural integrity and conformational switching capabilities.

36 citationstop 1%

protein structuredeep learning

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Molecular BiologybioRxivPreprintOct 26, 2021

The HIV-1 ribonucleoprotein dynamically regulates its condensate behavior and drives acceleration of protease activity through membraneless granular phase separation

Sébastien Lyonnais, S. Kashif Sadiq, Cristina Lorca-Oró…·Gilles Mirambeau

The paper investigates how HIV-1's RNP granules regulate protease activity through phase separation, revealing key RNA-binding motifs and their role in viral maturation.

3 citations

proteomicsmetagenomics

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